Human GUCY1A1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GUCY1A1
Locus ID	2982
Kit Components	GA102023G1, GUCY1A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102023G2, GUCY1A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102023G3, GUCY1A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000856, NM_001130682, NM_001130683, NM_001130684, NM_001130685, NM_001130686, NM_001130687, NM_001256449
Synonyms	GC-SA3; GUC1A3; GUCA3; GUCSA3; GUCY1A1; MYMY6
Summary	Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

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