Human ERp57 (PDIA3) activation kit by CRISPRa

CAT#: GA101978

PDIA3 CRISPRa kit - CRISPR gene activation of human protein disulfide isomerase family A member 3



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PDIA3 (ERp57) mouse monoclonal antibody, clone OTI3E1 (formerly 3E1)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


PDIA3 (Myc-DDK-tagged)-Human protein disulfide isomerase family A, member 3 (PDIA3)
    • 10 ug

CNY 3,760.00
CNY 3,990.00


Rabbit monoclonal anti-PDIA3 antibody for SISCAPA, clone OTIR5G4
    • 100 ul

CNY 4,390.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PDIA3
Locus ID 2923
Kit Components

GA101978G1, ERp57 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101978G2, ERp57 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101978G3, ERp57 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_005313
Synonyms ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC
Summary This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. [provided by RefSeq, Dec 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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