Human BLOC1S1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BLOC1S1
Locus ID	2647
Kit Components	GA101766G1, BLOC1S1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101766G2, BLOC1S1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101766G3, BLOC1S1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001487, NR_037655, NR_037656, NR_037657
Synonyms	BLOS1; GCN5L1; MICoA; RT14
Summary	BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 [PubMed 15102850]).[supplied by OMIM, Mar 2008]

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