Human CD16b (FCGR3B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FCGR3B
Locus ID	2215
Kit Components	GA101552G1, CD16b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101552G2, CD16b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101552G3, CD16b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000570, NM_001244753, NM_001271035, NM_001271036, NM_001271037
Synonyms	CD16; CD16b; FCG3; FCGR3; FCR-10; FCRIII; FCRIIIb
Summary	The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

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