Human Cortactin (CTTN) activation kit by CRISPRa
CAT#: GA101400
CTTN CRISPRa kit - CRISPR gene activation of human cortactin
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CTTN |
Locus ID | 2017 |
Kit Components | GA101400G1, Cortactin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101400G2, Cortactin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101400G3, Cortactin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001184740, NM_005231, NM_138565 |
Synonyms | EMS1 |
Summary | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN401111 | CTTN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |