Human EDG2 (LPAR1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LPAR1
Locus ID	1902
Kit Components	GA101325G1, EDG2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101325G2, EDG2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101325G3, EDG2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001401, NM_057159, NM_001351397, NM_001351398, NM_001351399, NM_001351400, NM_001351401, NM_001351402, NM_001351403, NM_001351404, NM_001351405, NM_001351406, NM_001351407, NM_001351408, NM_001351409, NM_001351410, NM_001351411, NM_001351412, NM_001351413, NM_001351414, NM_001351415, NM_001351416, NM_001351417, NM_001351418, NM_001351419, NM_001351420
Synonyms	edg-2; EDG2; Gpcr26; GPR26; LPA1; Mrec1.3; rec.1.3; vzg-1; VZG1
Summary	The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene. [provided by RefSeq, Oct 2020]

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