Human CYB5R3 activation kit by CRISPRa

CAT#: GA101197

CYB5R3 CRISPRa kit - CRISPR gene activation of human cytochrome b5 reductase 3



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
CYB5R3 mouse monoclonal antibody, clone OTI2A10 (formerly 2A10)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


CYB5R3 (Myc-DDK-tagged)-Human cytochrome b5 reductase 3 (CYB5R3), transcript variant 1
    • 10 ug

CNY 2,400.00
CNY 3,990.00


Rabbit Polyclonal anti-CYB5R3 Antibody
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CYB5R3
Locus ID 1727
Kit Components

GA101197G1, CYB5R3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101197G2, CYB5R3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101197G3, CYB5R3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000398, NM_001129819, NM_001171660, NM_001171661, NM_007326
Synonyms B5R; DIA1
Summary This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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