Human Deoxyguanosine kinase (DGUOK) activation kit by CRISPRa

CAT#: GA101191

DGUOK CRISPRa kit - CRISPR gene activation of human deoxyguanosine kinase



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-DGUOK Antibody
    • 100 ul

CNY 5,250.00


DGUOK (Myc-DDK-tagged)-Human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 1
    • 10 ug

CNY 2,400.00
CNY 3,990.00


DGUOK Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol DGUOK
Locus ID 1716
Kit Components

GA101191G1, Deoxyguanosine kinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101191G2, Deoxyguanosine kinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101191G3, Deoxyguanosine kinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001318859, NM_001318860, NM_001318861, NM_001318862, NM_001318863, NM_001929, NM_080915, NM_080916, NM_080917, NM_080918, NR_134893, NR_134894, NR_134895, NR_134896, NR_134897, NR_134898
Synonyms deoxyguanosine kinase; deoxyguanosine kinase, mitochondrial; dGK; OTTHUMP00000160251; OTTHUMP00000160252
Summary In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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