Human DHX8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DHX8
Locus ID	1659
Kit Components	GA101171G1, DHX8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101171G2, DHX8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101171G3, DHX8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001302623, NM_001322216, NM_001322217, NM_001322218, NM_001322219, NM_001322220, NM_001322221, NM_004941, NR_136225, NR_136226, NR_136227, NR_136228
Synonyms	DDX8; HRH1; PRP22; PRPF22
Summary	This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

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