Human Cytochrome P450 4A (CYP4A11) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CYP4A11
Locus ID	1579
Kit Components	GA101109G1, Cytochrome P450 4A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101109G2, Cytochrome P450 4A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101109G3, Cytochrome P450 4A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000778, NM_001319155, NR_134988, NR_134989, NR_134990, NR_134991, NR_134992, NR_134993, NR_134994, NM_001363587
Synonyms	CP4Y; CYP4A2; CYP4AII
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]

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