Human Mitochondrial dicarboxylate carrier (SLC25A10) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC25A10
Locus ID	1468
Kit Components	GA101036G1, Mitochondrial dicarboxylate carrier gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101036G2, Mitochondrial dicarboxylate carrier gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101036G3, Mitochondrial dicarboxylate carrier gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001270888, NM_001270953, NM_012140
Synonyms	DIC
Summary	This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

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