Human Nicotinic Acetylcholine Receptor beta 2 (CHRNB2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CHRNB2
Locus ID	1141
Kit Components	GA100818G1, Nicotinic Acetylcholine Receptor beta 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100818G2, Nicotinic Acetylcholine Receptor beta 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100818G3, Nicotinic Acetylcholine Receptor beta 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000748
Synonyms	EFNL3; nAChRB2
Summary	Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008]

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