Human Choline Acetyltransferase (CHAT) activation kit by CRISPRa

CAT#: GA100785

CHAT CRISPRa kit - CRISPR gene activation of human choline O-acetyltransferase



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
CHAT Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

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CHAT (Myc-DDK-tagged)-Human choline O-acetyltransferase (CHAT), transcript variant M
    • 10 ug

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CHAT Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CHAT
Locus ID 1103
Kit Components

GA100785G1, Choline Acetyltransferase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100785G2, Choline Acetyltransferase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100785G3, Choline Acetyltransferase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001142929, NM_001142933, NM_001142934, NM_020549, NM_020984, NM_020985, NM_020986
Synonyms CHOACTASE; CMS1A; CMS1A2
Summary This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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