Human CENPF activation kit by CRISPRa
CAT#: GA100767
CENPF CRISPRa kit - CRISPR gene activation of human centromere protein F
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CENPF |
Locus ID | 1063 |
Kit Components | GA100767G1, CENPF gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100767G2, CENPF gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100767G3, CENPF gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_005196, NM_016343 |
Synonyms | CENF; hcp-1; PRO1779 |
Summary | This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN414070 | CENPF - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |