Human CDK8 activation kit by CRISPRa
CAT#: GA100736
CDK8 CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase 8
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CDK8 |
Locus ID | 1024 |
Kit Components | GA100736G1, CDK8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100736G2, CDK8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100736G3, CDK8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001260, NM_001318368, NM_001346501 |
Synonyms | K35 |
Summary | This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN212592 | CDK8 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN212592BN | CDK8 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN212592LP | CDK8 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN212592RB | CDK8 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN412592 | CDK8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |