Human Calnexin (CANX) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CANX
Locus ID	821
Kit Components	GA100574G1, Calnexin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100574G2, Calnexin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100574G3, Calnexin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001024649, NM_001746, NM_001363996, NM_001364000, NM_001363995, NM_001363997, NM_001363999, NM_001363993, NM_001363994, NM_001363998, NM_001364001, NR_157048
Synonyms	CNX; IP90; P90
Summary	This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018]

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