Human BCKDHB activation kit by CRISPRa
CAT#: GA100408
BCKDHB CRISPRa kit - CRISPR gene activation of human branched chain keto acid dehydrogenase E1 subunit beta
CNY 12,255.00
CNY 3,656.00
CNY 3,990.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | BCKDHB |
Locus ID | 594 |
Kit Components | GA100408G1, BCKDHB gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100408G2, BCKDHB gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100408G3, BCKDHB gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_000056, NM_001318975, NM_183050, NR_134945 |
Synonyms | BCKDE1B; BCKDH E1-beta; E1B |
Summary | This gene encodes the E1 beta subunit of branched-chain keto acid dehydrogenase, which is a multienzyme complex associated with the inner membrane of mitochondria. This enzyme complex functions in the catabolism of branched-chain amino acids. Mutations in this gene have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation and feeding problems. Alternative splicing at this locus results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN408059 | BCKDHB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |