Human Apolipoprotein E (APOE) activation kit by CRISPRa

CAT#: GA100247

APOE CRISPRa kit - CRISPR gene activation of human apolipoprotein E



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Mouse Monoclonal ApoE4 Antibody (4E4)
    • 100 ul

CNY 5,381.00


APOE (Myc-DDK-tagged)-Human apolipoprotein E (APOE)
    • 10 ug

CNY 2,400.00
CNY 4,465.00


APOE mouse monoclonal antibody, clone OTI3B9 (formerly 3B9)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol APOE
Locus ID 348
Kit Components

GA100247G1, Apolipoprotein E gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100247G2, Apolipoprotein E gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100247G3, Apolipoprotein E gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000041, NM_001302688, NM_001302689, NM_001302690, NM_001302691
Synonyms AD2; APO-E; LDLCQ5; LPG
Summary The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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