Human AOC2 activation kit by CRISPRa

CAT#: GA100216

AOC2 CRISPRa kit - CRISPR gene activation of human amine oxidase copper containing 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
AOC2 Antibody - middle region
    • 100 ul

CNY 5,250.00


AOC2 (Myc-DDK-tagged)-Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2
    • 10 ug

CNY 5,536.00


AOC2 Antibody - middle region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol AOC2
Locus ID 314
Kit Components

GA100216G1, AOC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100216G2, AOC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100216G3, AOC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001158, NM_009590
Synonyms DAO2; RAO
Summary Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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