Human ABCD1 activation kit by CRISPRa

CAT#: GA100150

ABCD1 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily D member 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
ABCD1 mouse monoclonal antibody, clone OTI4C2 (formerly 4C2)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


ABCD1 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family D (ALD), member 1 (ABCD1)
    • 10 ug

CNY 5,456.00


Purified ABCD1 mouse monoclonal antibody, clone OTI5G6 (formerly 5G6)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ABCD1
Locus ID 215
Kit Components

GA100150G1, ABCD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100150G2, ABCD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100150G3, ABCD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000033
Synonyms ABC42; ALD; ALDP; AMN
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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