Human alpha Adducin (ADD1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADD1
Locus ID	118
Kit Components	GA100080G1, alpha Adducin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100080G2, alpha Adducin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100080G3, alpha Adducin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001119, NM_001286645, NM_014189, NM_014190, NM_176801, NM_001354754, NM_001354755, NM_001354756, NM_001354757, NM_001354758, NM_001354759, NM_001354761, NM_001354762
Synonyms	ADDA
Summary	Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]

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