Human ACAT1 (ACACA) activation kit by CRISPRa

CAT#: GA100023

ACACA CRISPRa kit - CRISPR gene activation of human acetyl-CoA carboxylase alpha



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
ACC1 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

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ACACA (Myc-DDK-tagged)-Human acetyl-CoA carboxylase alpha (ACACA), transcript variant 4
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ACC1 Rabbit polyclonal Antibody
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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ACACA
Locus ID 31
Kit Components

GA100023G1, ACAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100023G2, ACAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100023G3, ACAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000664, NM_198834, NM_198835, NM_198836, NM_198837, NM_198838, NM_198839
Synonyms ACAC; ACC; ACC, ACAC, ACC1, ACCA; ACC-alpha; ACC1; ACCA; acetyl-CoA carboxylase-alpha; acetyl-CoA carboxylase 1; acetyl-Coenzyme A carboxylase alpha; OTTHUMP00000164069
Summary Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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