Human ACAT1 (ACACA) activation kit by CRISPRa
CAT#: GA100023
ACACA CRISPRa kit - CRISPR gene activation of human acetyl-CoA carboxylase alpha
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | ACACA |
Locus ID | 31 |
Kit Components | GA100023G1, ACAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100023G2, ACAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100023G3, ACAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_000664, NM_198834, NM_198835, NM_198836, NM_198837, NM_198838, NM_198839 |
Synonyms | ACAC; ACC; ACC, ACAC, ACC1, ACCA; ACC-alpha; ACC1; ACCA; acetyl-CoA carboxylase-alpha; acetyl-CoA carboxylase 1; acetyl-Coenzyme A carboxylase alpha; OTTHUMP00000164069 |
Summary | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN416721 | ACACA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |