Human NAT1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NAT1
Locus ID	9
Kit Components	GA100003G1, NAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100003G2, NAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100003G3, NAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000662, NM_001160170, NM_001160171, NM_001160172, NM_001160173, NM_001160174, NM_001160175, NM_001160176, NM_001160179, NM_001291962
Synonyms	AAC1; MNAT; NAT-1; NATI
Summary	This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

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