AMHR2 (NM_020547) Human Mutant ORF Clone
CAT#: RC403210
- TrueORF®
AMHR2 Mutant (R80X), Myc-DDK-tagged ORF clone of Homo sapiens anti-Mullerian hormone receptor, type II (AMHR2), transcript variant 1 as transfection-ready DNA
Need custom modification / cloning service?
Get a free quote
CNY 3,990.00
货期*
3周
规格
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Product Name | AMHR2 (NM_020547) Human Mutant ORF Clone |
Mutation Description | R80X |
Affected Codon# | 80 |
Affected NT# | 238 |
Nucleotide Mutation | AMHR2 Mutant (R80X), Myc-DDK-tagged ORF clone of Homo sapiens anti-Mullerian hormone receptor, type II (AMHR2), transcript variant 1 as transfection-ready DNA |
Effect | Persisen Mullerin dus syndrome |
Synonyms | AMHR; MISR2; MISRII; MRII |
Vector | pCMV6-Entry |
Tag | Myc-DDK |
ACCN | NM_020547 |
ORF Size | 237 bp |
Sequence Data |
>RC403210 representing NM_020547
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTAGGGTCTTTGGGGCTTTGGGCATTACTTCCCACAGCTGTGGAAGCACCCCCAAACAGGCGAACCT GTGTGTTCTTTGAGGCCCCTGGAGTGCGGGGAAGCACAAAGACACTGGGAGAGCTGCTAGATACAGGCAC AGAGCTCCCCAGAGCTATCCGCTGCCTCTACAGCCGCTGCTGCTTTGGGATCTGGAACCTGACCCAAGAC CGGGCACAGGTGGAAATGCAAGGATGC AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGA TAAGGTTTAA >RC403210 representing NM_020547
Red=Cloning site Green=Tags(s) MLGSLGLWALLPTAVEAPPNRRTCVFFEAPGVRGSTKTLGELLDTGTELPRAIRCLYSRCCFGIWNLTQD RAQVEMQGC SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NP_065434 |
RefSeq Size | 237 bp |
RefSeq ORF | 1722 bp |
Locus ID | 269 |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
MW | 8.7 kDa |
Gene Summary | This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
You may also need
Customer
Reviews
Loading...