PKN beta (PKN3) (NM_013355) Human Mutant ORF Clone

Specifications

Product Data
Product Name	PKN beta (PKN3) (NM_013355) Human Mutant ORF Clone
Mutation Description	W346X
Affected Codon#	346
Affected NT#	1038
Nucleotide Mutation	PKN3 Mutant (W346X), Myc-DDK-tagged ORF clone of Homo sapiens protein kinase N3 (PKN3) as transfection-ready DNA
Effect	Poenil proein defiieny
Synonyms	UTDP4-1
Vector	pCMV6-Entry
Tag	Myc-DDK
ACCN	NM_013355
ORF Size	1035 bp
Sequence Data	ORF Nucleotide Sequence (showhide) >RC403205 representing NM_013355 Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGAGGGGGCGCCGCGGCAGCCTGGGCCGAGCCAGTGGCCCCCAGAGGATGAGAAGGAGGTGATCC GCCGGGCCATCCAGAAAGAGCTGAAGATCAAGGAGGGGGTGGAGAACCTGCGGCGCGTGGCCACAGACCG CCGCCACTTGGGCCATGTGCAGCAGCTGCTGCGGTCCTCCAACCGCCGCCTGGAGCAGCTGCATGGCGAG CTGCGGGAGCTGCACGCCCGAATCCTGCTGCCCGGCCCTGGGCCTGGCCCAGCTGAGCCTGTGGCCTCAG GACCCCGGCCGTGGGCAGAGCAGCTCAGGGCTCGGCACCTAGAGGCTCTCCGGAGGCAGCTGCATGTGGA GCTGAAGGTGAAGCAGGGGGCTGAGAACATGACCCACACGTGCGCCAGTGGCACCCCCAAGGAGAGGAAG CTCCTGGCAGCTGCCCAGCAGATGCTGCGGGACAGCCAGCTGAAGGTGGCCCTGCTGCGGATGAAGATCA GCAGCCTGGAGGCCAGTGGGTCCCCGGAGCCAGGGCCTGAGCTGCTGGCGGAGGAGCTACAGCATCGACT GCACGTTGAGGCAGCTGTGGCTGAGGGCGCCAAGAACGTGGTGAAACTGCTTAGTAGCCGGAGAACACAG GACCGCAAGGCACTGGCTGAGGCCCAGGCCCAGCTACAGGAGTCCTCTCAGAAACTGGACCTCCTGCGCC TGGCCTTGGAGCAGCTGCTGGAGCAACTGCCTCCTGCCCACCCTTTGCGCAGCAGAGTGACCCGAGAGTT GCGGGCTGCGGTGCCTGGATACCCCCAGCCTTCAGGGACACCTGTGAAGCCCACCGCCCTAACAGGGACA CTGCAGGTCCGCCTCCTGGGCTGTGAACAGTTGCTGACAGCCGTGCCTGGGCGCTCCCCAGCGGCCGCAC TGGCCAGCAGCCCCTCCGAGGGCTGGCTTCGGACCAAGGCCAAGCACCAGCGTGGCCGAGGCGAGCTTGC CAGCGAGGTGCTGGCTGTGCTAAAGGTGGACAACCGTGTTGTGGGGCAGACGGGC AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGA TAAGGTTTAA Protein Sequence (showhide) >RC403205 representing NM_013355 Red=Cloning site Green=Tags(s) MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSSNRRLEQLHGE LRELHARILLPGPGPGPAEPVASGPRPWAEQLRARHLEALRRQLHVELKVKQGAENMTHTCASGTPKERK LLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLAEELQHRLHVEAAVAEGAKNVVKLLSSRRTQ DRKALAEAQAQLQESSQKLDLLRLALEQLLEQLPPAHPLRSRVTRELRAAVPGYPQPSGTPVKPTALTGT LQVRLLGCEQLLTAVPGRSPAAALASSPSEGWLRTKAKHQRGRGELASEVLAVLKVDNRVVGQTG SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	NP_037487
RefSeq Size	1035 bp
RefSeq ORF	2670 bp
Locus ID	29941
Protein Families	Druggable Genome, Protein Kinase
MW	38 kDa
Gene Summary	Contributes to invasiveness in malignant prostate cancer.[UniProtKB/Swiss-Prot Function]

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