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Erlin2 (NM_001106088) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR212952L3V
- LentiORF®
-
Lenti ORF particles, Erlin2 (Myc-DDK-tagged ORF) - Rat ER lipid raft associated 2 (Erlin2), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Erlin2 (NM_001106088) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | RGD1309010; Spfh2 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001106088 |
| ORF Size | 1017 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR212952).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001106088.2, NP_001099558.1 |
| RefSeq Size | 3247 bp |
| RefSeq ORF | 1020 bp |
| Locus ID | 290823 |
| Gene Summary | Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (By similarity).[UniProtKB/Swiss-Prot Function] |
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