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Erlin2 (NM_001106088) Rat Untagged Clone
CAT＃: RN212952
Erlin2 (untagged ORF) - Rat ER lipid raft associated 2 (Erlin2), (10 ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | RGD1309010; Spfh2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN212952 representing NM_001106088
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCTCAATTGGGAGCAGTTGTGGCTGTGGCTTCCAGTTTCTTTTGCGCATCTCTCTTCTCAGCTGTGC ACAAGATAGAAGAGGGACATATCGGAGTATATTACAGAGGTGGTGCCCTGCTGACCTCCACCAGTGGCCC AGGTTTCCATCTCATGCTCCCGTTCATCACATCCTACAAGTCTGTACAGACCACTCTCCAAACGGATGAA GTGAAGAACGTACCATGCGGAACCAGTGGTGGTGTGATGATCTACTTTGACAGAATTGAAGTGGTGAACT TCCTGGTCCCACATGCAGTGTATGATATAGTGAAGAACTATACTGCAGACTATGACAAGGCCCTCATCTT CAACAAGATTCATCATGAGCTTAACCAGTTCTGCAGCGTCCATACACTTCAGGAAGTCTATATCGAGCTG TTTGATCAAATCGATGAAAACCTCAAATTGGCTTTGCAGCAGGACCTGACCTCCATGGCCCCTGGGCTTG TTATCCAAGCTGTACGAGTGACAAAGCCCAACATCCCTGAGGCAATCCGCAGGAACTATGAGTTGATGGA AAGCGAGAAGACGAAGCTTCTCATTGCGGCCCAGAAACAGAAGGTGGTGGAGAAGGAGGCGGAAACGGAG AGGAAGAAGGCCCTCATTGAGGCAGAAAAAGTGGCACAGGTTGCAGAAATCACCTATGGGCAGAAGGTGA TGGAGAAGGAGACTGAGAAGAAGATTTCAGAAATTGAGGATGCTGCATTTCTGGCCCGGGAGAAGGCAAA GGCCGATGCTGAGTGCTACACTGCTCTGAAGATCGCGGAAGCCAATAAGCTCAAGCTGACCCCAGAATAC CTGCAGCTGATGAAGTACAAGGCTATTGCTTCCAACAGCAAGATTTACTTTGGCAAAGACATCCCCAACA TGTTCATGGACTCCGCAGGCGGCCTGGGCAAGCAGTCTGAGGGGCTGAGTGACAAGCTGGGCTTTGGCCT AGAAGACGAGCCCCTAGAGACAGCCACAAAGGATAATTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001106088 |
| Insert Size | 1020 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001106088.2, NP_001099558.1 |
| RefSeq Size | 3247 bp |
| RefSeq ORF | 1020 bp |
| Locus ID | 290823 |
| UniProt ID | B5DEH2 |
| Gene Summary | Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR212952 | Erlin2 (Myc-DDK-tagged ORF) - Rat ER lipid raft associated 2 (Erlin2), (10 ug) |
CNY 3,990.00 |
|
| RR212952L3 | Lenti ORF clone of Erlin2 (Myc-DDK-tagged ORF) - Rat ER lipid raft associated 2 (Erlin2), (10 ug) |
CNY 6,080.00 |
|
| RR212952L4 | Lenti ORF clone of Erlin2 (mGFP-tagged ORF) - Rat ER lipid raft associated 2 (Erlin2), (10 ug) |
CNY 6,650.00 |
