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Rnf5 (NM_001109025) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR211028L3V
- LentiORF®
-
Lenti ORF particles, Rnf5 (Myc-DDK-tagged ORF) - Rat ring finger protein 5 (Rnf5), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Rnf5 (NM_001109025) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | MGC109637 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001109025 |
| ORF Size | 540 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR211028).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001109025.2, NP_001102495.1 |
| RefSeq Size | 1142 bp |
| RefSeq ORF | 543 bp |
| Locus ID | 407784 |
| Gene Summary | Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation; the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses.[UniProtKB/Swiss-Prot Function] |
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