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Ppargc1b (NM_176075) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR209465L4V
- LentiORF®
-
Lenti ORF particles, Ppargc1b (GFP-tagged ORF) - Rat peroxisome proliferator-activated receptor gamma, coactivator 1 beta (Ppargc1b), 200ul, >10^7 TU/mL
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CNY 16,720.00
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Specifications
| Product Data | |
| Product Name | Ppargc1b (NM_176075) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | Perc; PGC1beta |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_176075 |
| ORF Size | 2970 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR209465).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_176075.2, NP_788264.1 |
| RefSeq Size | 3163 bp |
| RefSeq ORF | 2973 bp |
| Locus ID | 291567 |
| Gene Summary | Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be part of the pathways regulating the elevation of gluconeogenesis, beta-oxidation of fatty acids and ketogenesis during fasting. Stimulates SREBP-mediated lipogenic gene expression in the liver. Induces energy expenditure and antagonizes obesity when overexpressed. Induces also the expression of mitochondrial genes involved in oxidative metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.[UniProtKB/Swiss-Prot Function] |
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