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Pif1 (NM_001044253) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR207530L3V
- LentiORF®
-
Lenti ORF particles, Pif1 (Myc-DDK-tagged ORF) - Rat Pif1/Rrm3 DNA-helicase-like protein (Pif1), 200ul, >10^7 TU/mL
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CNY 11,077.00
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Specifications
| Product Data | |
| Product Name | Pif1 (NM_001044253) Rat Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001044253 |
| ORF Size | 1911 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR207530).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001044253.1, NP_001037718.1 |
| RefSeq Size | 1915 bp |
| RefSeq ORF | 1914 bp |
| Locus ID | 367645 |
| Gene Summary | DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.[UniProtKB/Swiss-Prot Function] |
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