Klhl25 (NM_001039006) Rat Tagged ORF Clone Lentiviral Particle

CAT＃: RR206142L4V

  • LentiORF®

Lenti ORF particles, Klhl25 (GFP-tagged ORF) - Rat kelch-like 25 (Drosophila) (Klhl25), 200ul, >10^7 TU/mL

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CNY 11,780.00

货期*
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规格
    • 200 ul

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经常一起买 (2)
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Specifications

Product Data
Product Name Klhl25 (NM_001039006) Rat Tagged ORF Clone Lentiviral Particle
Synonyms RGD1310815
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001039006
ORF Size 1767 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RR206142).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001039006.1, NP_001034095.1
RefSeq Size 3303 bp
RefSeq ORF 1770 bp
Locus ID 293023
Gene Summary Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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