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Tollip (NM_001109668) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR204753L3V
- LentiORF®
-
Lenti ORF particles, Tollip (Myc-DDK-tagged ORF) - Rat toll interacting protein (Tollip), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Tollip (NM_001109668) Rat Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001109668 |
| ORF Size | 822 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR204753).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001109668.1, NP_001103138.1 |
| RefSeq Size | 3795 bp |
| RefSeq ORF | 825 bp |
| Locus ID | 361677 |
| Gene Summary | Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity).[UniProtKB/Swiss-Prot Function] |
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