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Tollip (NM_001109668) Rat Tagged ORF Clone
CAT＃: RR204753
- TrueORF®
Tollip (Myc-DDK-tagged ORF) - Rat toll interacting protein (Tollip), (10 ug)
"NM_001109668" in other vectors (3)
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CNY 3,990.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Rat Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RR204753 representing NM_001109668
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGACCACCGTCAGCACGCAGCGCGGGCCGGTATACATTGGTGAGCTCCCCCAGGACTTTCTCCGTA TAACGCCCACACAGCAGCAGCAGCAGATACAGCTGGATGCCCAGGCAGCCCAGCAGCTGCAGTATGGAGG AGCAGTTGGCACTGTGGGTCGTCTCAGCATCACTGTAGTACAGGCCAAATTGGCAAAGAATTATGGCATG ACTCGTATGGACCCTTACTGCCGCCTGCGTCTGGGCTATGCTGTTTATGAAACTCCCACAGCACACAATG GCGCCAAGAACCCTCGATGGAACAAGGTTATTCAGTGCACAGTGCCCCCAGGTGTGGACTCGTTCTACCT TGAGATCTTCGATGAGCGAGCCTTCTCCATGGACGACCGCATAGCTTGGACCCACATCACTATCCCCGAG TCCCTGAAGCAGGGCCAAGTGGAGGACGAGTGGTATAGCCTGAGTGGGAGGCAGGGCGACGACAAGGAGG GCATGATTAACCTGGTCATGTCCTATACGTCCCTTCCAGCTGCCATGATGATGCCGCCTCAGCCTGTGGT TCTGATGCCAACTGTGTACCAGCAGGGTGTTGGCTATGTGCCCATTGCAGGGATGCCTGCTGTCTGCAGC CCTGGCATGGTGCCTATGGCTATGCCCCCACCAGCTGTGGCTCCTCAGCCCCGCTGTAATGAGGAGGACC TCAAGGCTATCCAGGACATGTTTCCCAACATGGACAGGGAAGTAATCCGTTCTGTGCTTGAAGCCCAAAG AGGGAACAAAGATGCTGCCATCAACTCCTTACTGCAAATGGGCGAAGAGTCC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RR204753 representing NM_001109668
Red=Cloning site Green=Tags(s) MATTVSTQRGPVYIGELPQDFLRITPTQQQQQIQLDAQAAQQLQYGGAVGTVGRLSITVVQAKLAKNYGM TRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHITIPE SLKQGQVEDEWYSLSGRQGDDKEGMINLVMSYTSLPAAMMMPPQPVVLMPTVYQQGVGYVPIAGMPAVCS PGMVPMAMPPPAVAPQPRCNEEDLKAIQDMFPNMDREVIRSVLEAQRGNKDAAINSLLQMGEES TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001109668 |
| ORF Size | 822 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001109668.1, NP_001103138.1 |
| RefSeq Size | 3795 bp |
| RefSeq ORF | 825 bp |
| Locus ID | 361677 |
| UniProt ID | A2RUW1 |
| MW | 30.3 kDa |
| Gene Summary | Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RN204753 | Tollip (untagged ORF) - Rat toll interacting protein (Tollip), (10 ug) |
CNY 3,990.00 |
|
| RR204753L3 | Lenti ORF clone of Tollip (Myc-DDK-tagged ORF) - Rat toll interacting protein (Tollip), (10 ug) |
CNY 6,080.00 |
|
| RR204753L4 | Lenti ORF clone of Tollip (mGFP-tagged ORF) - Rat toll interacting protein (Tollip), (10 ug) |
CNY 6,650.00 |
