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GLRB (NM_001166061) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC228238L4V
- LentiORF®
-
Lenti ORF particles, GLRB (mGFP-tagged)-Human glycine receptor, beta (GLRB), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 9,120.00
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Specifications
| Product Data | |
| Product Name | GLRB (NM_001166061) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | HKPX2 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001166061 |
| ORF Size | 909 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC228238).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001166061.1, NP_001159533.1 |
| RefSeq ORF | 912 bp |
| Locus ID | 2743 |
| Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| MW | 34.94 kDa |
| Gene Summary | This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
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