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PTPN12 (NM_001131009) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC226061L4V
- LentiORF®
-
Lenti ORF particles, PTPN12 (mGFP-tagged)-Human protein tyrosine phosphatase, non-receptor type 12 (PTPN12), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | PTPN12 (NM_001131009) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | PTP-PEST; PTPG1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001131009 |
| ORF Size | 1950 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC226061).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001131009.1 |
| RefSeq Size | 3026 bp |
| RefSeq ORF | 1953 bp |
| Locus ID | 5782 |
| Protein Families | Druggable Genome, Phosphatase |
| MW | 72.8 kDa |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
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