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IL21 Receptor (IL21R) (NM_181079) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC224395L4V
- LentiORF®
-
Lenti ORF particles, IL21R (mGFP-tagged) - Human interleukin 21 receptor (IL21R), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | IL21 Receptor (IL21R) (NM_181079) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CD360; IMD56; NILR |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_181079 |
| ORF Size | 1614 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC224395).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_181079.1 |
| RefSeq Size | 5006 bp |
| RefSeq ORF | 1683 bp |
| Locus ID | 50615 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
| MW | 59.1 kDa |
| Gene Summary | The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] |
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