OGDH (NM_001003941) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC224183L3V
- LentiORF®
Lenti ORF particles, OGDH (Myc-DDK tagged) - Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,645.00
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Specifications
Product Data | |
Product Name | OGDH (NM_001003941) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | AKGDH; E1k; KGD1; OGDC; OGDH2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001003941 |
ORF Size | 1281 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC224183).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001003941.1 |
RefSeq Size | 1791 bp |
RefSeq ORF | 1284 bp |
Locus ID | 4967 |
Protein Families | Druggable Genome |
Protein Pathways | Citrate cycle (TCA cycle), Lysine degradation, Metabolic pathways, Tryptophan metabolism |
MW | 48.18 kDa |
Gene Summary | This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009] |
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