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CHRNA10 (NM_020402) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC222267L4V
- LentiORF®
-
Lenti ORF particles, CHRNA10 (mGFP-tagged) - Human cholinergic receptor, nicotinic, alpha 10 (CHRNA10), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | CHRNA10 (NM_020402) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_020402 |
| ORF Size | 1350 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC222267).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_020402.2 |
| RefSeq Size | 1962 bp |
| RefSeq ORF | 1353 bp |
| Locus ID | 57053 |
| Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
| MW | 49.5 kDa |
| Gene Summary | Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.[UniProtKB/Swiss-Prot Function] |
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