TLR8 (NM_138636) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC221986L1V
- LentiORF®
-
Lenti ORF particles, TLR8 (Myc-DDK tagged) - Human toll-like receptor 8 (TLR8), 200ul, >10^7 TU/mL
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CNY 11,210.00
货期*
详询
规格
Cited in 2 publications. |
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经常一起买 (3)
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Specifications
Product Data | |
Product Name | TLR8 (NM_138636) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CD288 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_138636 |
ORF Size | 3123 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221986).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_138636.2 |
RefSeq Size | 4211 bp |
RefSeq ORF | 3126 bp |
Locus ID | 51311 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Toll-like receptor signaling pathway |
MW | 119.6 kDa |
Gene Summary | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Toll-Like Receptor 8 Agonist Strengthens the Protective Efficacy of ESAT-6 Immunization to Mycobacterium tuberculosis Infection
,null,
Frontiers in Immunology
,PubMed ID 29416532
[TLR8]
|
Placental Toll-Like Receptor 3 and Toll-Like Receptor 7/8 Activation Contributes to Preeclampsia in Humans and Mice
,null,
PLoS ONE
,PubMed ID 22848646
[TLR8]
|
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