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PIMT (TGS1) (NM_024831) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC221904L3V
- LentiORF®
-
Lenti ORF particles, TGS1 (Myc-DDK-tagged)-Human trimethylguanosine synthase 1 (TGS1), 200ul, >10^7 TU/mL
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CNY 15,485.00
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规格
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Specifications
| Product Data | |
| Product Name | PIMT (TGS1) (NM_024831) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | NCOA6IP; PIMT; PIPMT |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_024831 |
| ORF Size | 2559 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC221904).
|
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_024831.6 |
| RefSeq Size | 3708 bp |
| RefSeq ORF | 2562 bp |
| Locus ID | 96764 |
| Protein Families | Druggable Genome |
| MW | 96.6 kDa |
| Gene Summary | Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.[UniProtKB/Swiss-Prot Function] |
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