EVI1 (MECOM) (NM_005241) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC221770L4V
- LentiORF®
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Lenti ORF particles, MECOM (mGFP-tagged) - Human MDS1 and EVI1 complex locus (MECOM), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 12,540.00
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规格
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Specifications
Product Data | |
Product Name | EVI1 (MECOM) (NM_005241) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | AML1-EVI-1; EVI1; KMT8E; MDS1; MDS1-EVI1; PRDM3; RUSAT2 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_005241 |
ORF Size | 3153 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221770).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_005241.1 |
RefSeq Size | 3570 bp |
RefSeq ORF | 3156 bp |
Locus ID | 2122 |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Chronic myeloid leukemia, MAPK signaling pathway, Pathways in cancer |
MW | 118.1 kDa |
Gene Summary | The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
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