United States
Germany
Japan
United Kingdom
China
GDNF (NM_000514) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC221376L4V
- LentiORF®
-
Lenti ORF particles, GDNF (mGFP-tagged) - Human glial cell derived neurotrophic factor (GDNF), transcript variant 1, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,360.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | GDNF (NM_000514) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ATF; ATF1; ATF2; HFB1-GDNF; HSCR3 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_000514 |
| ORF Size | 633 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC221376).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000514.2 |
| RefSeq Size | 836 bp |
| RefSeq ORF | 636 bp |
| Locus ID | 2668 |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| MW | 23.72 kDa |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
