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WNK3 (NM_001002838) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC220755L1V
- LentiORF®
-
Lenti ORF particles, WNK3 (Myc-DDK tagged) - Human WNK lysine deficient protein kinase 3 (WNK3), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 21,660.00
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规格
| Cited in 2 publications. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | WNK3 (NM_001002838) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | PRKWNK3 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_001002838 |
| ORF Size | 5229 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC220755).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001002838.1 |
| RefSeq Size | 7572 bp |
| RefSeq ORF | 5232 bp |
| Locus ID | 65267 |
| Protein Families | Druggable Genome, Protein Kinase |
| MW | 191.6 kDa |
| Gene Summary | This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway
,null,
American Journal of Physiology - Renal Physiology
,PubMed ID 18768590
[WNK3]
|
|
WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis
,null,
,PubMed ID 16275913
[WNK3]
|
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