Integrin beta 4 (ITGB4) (NM_000213) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC220541L1V

  • LentiORF®

Lenti ORF particles, ITGB4 (Myc-DDK tagged) - Human integrin, beta 4 (ITGB4), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 21,660.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Integrin beta 4 (ITGB4) (NM_000213) Human Tagged ORF Clone Lentiviral Particle
Synonyms CD104; GP150
Vector pLenti-C-Myc-DDK
ACCN NM_000213
ORF Size 5466 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC220541).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000213.3
RefSeq Size 5925 bp
RefSeq ORF 5469 bp
Locus ID 3691
Domains INB, Calx-beta, PSI, FN3, EGF
Protein Families Druggable Genome
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton
MW 202.12 kDa
Gene Summary Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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