gamma Sarcoglycan (SGCG) (NM_000231) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC220093L3V
- LentiORF®
Lenti ORF particles, SGCG (Myc-DDK tagged) - Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG), 200ul, >10^7 TU/mL
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CNY 8,170.00
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Specifications
Product Data | |
Product Name | gamma Sarcoglycan (SGCG) (NM_000231) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | 35DAG; A4; DAGA4; DMDA; DMDA1; gamma-SG; LGMD2C; LGMDR5; MAM; SCARMD2; SCG3 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_000231 |
ORF Size | 873 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220093).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000231.1, NP_000222.1 |
RefSeq Size | 1661 bp |
RefSeq ORF | 876 bp |
Locus ID | 6445 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis |
MW | 32.4 kDa |
Gene Summary | This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008] |
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