United States
Germany
Japan
United Kingdom
China
MBD2 (NM_015832) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC218349L3V
- LentiORF®
-
Lenti ORF particles, MBD2 (Myc-DDK tagged) - Human methyl-CpG binding domain protein 2 (MBD2), transcript variant 2, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,170.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | MBD2 (NM_015832) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | DMTase; NY-CO-41 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_015832 |
| ORF Size | 906 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC218349).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_015832.3 |
| RefSeq Size | 1357 bp |
| RefSeq ORF | 909 bp |
| Locus ID | 8932 |
| Domains | MBD |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| MW | 31.6 kDa |
| Gene Summary | DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
