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ARID1A (NM_006015) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC218151L1V
- LentiORF®
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Lenti ORF particles, ARID1A (Myc-DDK tagged) - Human AT rich interactive domain 1A (SWI-like) (ARID1A), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 21,660.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Product Name | ARID1A (NM_006015) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | B120; BAF250; BAF250a; BM029; C1orf4; CSS2; ELD; hELD; hOSA1; MRD14; OSA1; P270; SMARCF1 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_006015 |
| ORF Size | 6855 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC218151).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_006015.3 |
| RefSeq Size | 8595 bp |
| RefSeq ORF | 6858 bp |
| Locus ID | 8289 |
| Protein Families | Druggable Genome |
| MW | 241.9 kDa |
| Gene Summary | This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Identification and functional characterization of a novel bipartite nuclear localization sequence in ARID1A.
,null,
Biochemical and biophysical research communications
,PubMed ID 26614907
[ARID1A]
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