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LAMA3 (NM_198129) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC215949L1V
- LentiORF®
-
Lenti ORF particles, LAMA3 (Myc-DDK tagged) - Human laminin, alpha 3 (LAMA3), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 21,660.00
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Specifications
| Product Data | |
| Product Name | LAMA3 (NM_198129) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | BM600; E170; LAMNA; LOCS |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_198129 |
| ORF Size | 9999 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC215949).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_198129.1, NP_937762.1 |
| RefSeq Size | 10511 bp |
| RefSeq ORF | 10002 bp |
| Locus ID | 3909 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer |
| MW | 366.5 kDa |
| Gene Summary | The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014] |
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