MYO3A (NM_017433) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC215401L4V
- LentiORF®
Lenti ORF particles, MYO3A (mGFP-tagged)-Human myosin IIIA (MYO3A), 200ul, >10^7 TU/mL
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CNY 24,035.00
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Specifications
Product Data | |
Product Name | MYO3A (NM_017433) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | DFNB30 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_017433 |
ORF Size | 4848 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC215401).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_017433.3 |
RefSeq Size | 5597 bp |
RefSeq ORF | 4851 bp |
Locus ID | 53904 |
Protein Families | Druggable Genome, Protein Kinase |
MW | 186 kDa |
Gene Summary | The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq, Jul 2008] |
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