MANEA (NM_024641) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC214726L4V
- LentiORF®
-
Lenti ORF particles, MANEA (mGFP-tagged) - Human mannosidase, endo-alpha (MANEA), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | MANEA (NM_024641) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | ENDO; hEndo |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_024641 |
ORF Size | 1386 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC214726).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_024641.2 |
RefSeq Size | 4593 bp |
RefSeq ORF | 1389 bp |
Locus ID | 79694 |
Protein Families | Transmembrane |
MW | 53.5 kDa |
Gene Summary | N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008] |
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